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KMID : 0356420000180020139
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Journal of Korean Andrology
2000 Volume.18 No. 2 p.139 ~ p.142
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Priapism Lasting for Over 24 hours Induced by Intracavernous Vasoactive Agents
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Han Jun-Hyun
Seo Kyung-Keun
Kim Sae-Chul
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Abstract
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Purpose: Retrospective study was done to evaluate the causes of priapism lasting for over 24 hours induced by intracavernous vasoactive agents. Materials and Methods: Thirteen patients of priapism lasting for 24-60 hours, induced by intracavernous vasoactive drugs, were retrospectively evaluated using medical records or by telephone interviews. Injected vasoactive drugs, providers of the drugs, purpose of the injection, reasons leaving the priapism untreated so long,
treatment modalities of priapism, and change of potency after the treatment were evaluated.
Results: Only 2 patients (15.4%) were self-injected to treat erectile dysfunction by doctor’s prescription. The others, who receved the drugs with out
doctor’s prescription, had injections to enhance their potency (46.1%, n=6) or to treat premature ejaculation (15.4%), n=2). The drugs injected were papaverine (23.1%, n=3), papaverine and phentolamine (23.1%, n=3) or prostaglandin E1 (7.7%,
n=1), but unknown in 6 (46.1%). The reasons of leaving the priapism untreated were mostly due to lack of no knowledge about the priapism (53.8%, n=7). Aspiration and irrigation with α-agonist of corpus cavernosum were applied to all patients. Four
patients who did not respond to the treatment underwent shunt operations. All the patients complained of weakened potency after the priapism.
Conclusions: Priapism lasting for over 24 hours induced by intracavernous vasoactive drugs were mostly due to abuse or misuse of the drugs and resulted in weakened potency. To avoid this disaster, the drugs should be given to patients by doctor’s prescription with full explanation about the side effects of the drug.
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KEYWORD
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Priapism, Vasoactive drug, Intracavernosal injection,
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